Four decades ago, humans achieved something previously thought impossible in a feat that would change lives around the world. The first successful heart transplant, which took place at Cambridge's Papworth Hospital, was lauded as a success.
The patient, Keith Castle, who was 52 at the time of surgery, went on to live for a further five years.
Although others patients had come before him, none had survived and been discharged from hospital after having the procedure.
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